Stability of cefdinir (CI-983, FK482) to extendedspectrum plasmid-mediated -lactamases

Kinetic Properties of Four Plasmid-Mediated AmpC -Lactamases

Kinetic Properties of Four Plasmid-Mediated AmpC -Lactamases Cédric Bauvois, Akiko Shimizu Ibuka, Almeida Celso, Jimena Alba, Yoshikazu Ishii, Jean-Marie Frère, and Moreno Galleni* Centre d’Ingénierie des Protéines, Université de Liège, Sart Tilman, Belgium; Department of Food and Nutritional Sciences, University of Shizuoka, 52-1 Yada, Shizuoka 422-8526, Japan; and Department of Microbiology, ...

Plasmid-mediated carbencillin hydrolyzing beta-lactamases of Proteus mirabilis.

Since ABRAHAM and CHAIN') reported the production of beta((l)-lactamase by Escherichia coli, penicillinases have been shown to play an important role in the resistance of organisms against (3lactam antibiotics2.3). In many cases, the 46lactamases of Gram-negative bacteria have been shown to be mediated by R plasmids'), in contrast to chromosomally encoded drug resistance'). 46-Lactamases of Pro...

PCR Detection of Plasmid Mediated TEM, SHV and AmpC β-Lactamases in Community and Nosocomial Urinary Isolates of Escherichia coli

Plasmid-mediated beta-lactamases in clinical isolates of Klebsiella pneumoniae and Escherichia coli resistant to ceftazidime.

Low-level transferable resistance to ceftazidime was detected in seven strains of Klebsiella pneumoniae and one strain of Escherichia coli. Six of the Klebsiella strains and the E. coli strain were shown to produce a novel beta-lactamase (CAZ-lo) with a pI of 5.6 that hydrolyzed broad-spectrum cephalosporins at low but comparable levels. One strain of K. pneumoniae was of a serotype different f...

Extended-Spectrum-Beta-Lactamases, AmpC Beta-Lactamases and Plasmid Mediated Quinolone Resistance in Klebsiella spp. from Companion Animals in Italy

We report the genetic characterization of 15 Klebsiella pneumoniae (KP) and 4 isolates of K. oxytoca (KO) from clinical cases in dogs and cats and showing extended-spectrum cephalosporin (ESC) resistance. Extended spectrum beta-lactamase (ESBL) and AmpC genes, plasmid-mediated quinolone resistance (PMQR) and co-resistances were investigated. Among KP isolates, ST101 clone was predominant (8/15,...